| 英文名稱 | Lifitegrast; SAR 1118 |
|---|---|
| 中文名稱 | 立他司特 |
| CAS號 | 1025967-78-5 |
| 分子式 | C29H24Cl2N2O7S |
| 分子量 | 615.48 |
| 外觀 | White to off-white powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名稱 | Lifitegrast; SAR 1118 |
|---|---|
| 中文名稱 | 立他司特 |
| CAS號 | 1025967-78-5 |
| 分子式 | C29H24Cl2N2O7S |
| 分子量 | 615.48 |
| 外觀 | White to off-white powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses.