| 英文名稱 | Epothilone A |
|---|---|
| 中文名稱 | 埃博霉素A |
| CAS號 | 152044-53-6 |
| 分子式 | C26H39NO6S |
| 分子量 | 493.66 |
| 外觀 | White to off-white powder |
| 儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
| 英文名稱 | Epothilone A |
|---|---|
| 中文名稱 | 埃博霉素A |
| CAS號 | 152044-53-6 |
| 分子式 | C26H39NO6S |
| 分子量 | 493.66 |
| 外觀 | White to off-white powder |
| 儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.
PMID: 8999970 DOI: 10.1074/jbc.272.4.2534
Novel microtubule-targeting agents - the epothilones.
PMID: 19707459 PMCID: PMC2727900 DOI: 10.2147/btt.s3487