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規(guī)格	庫存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
500 mg	In-stock	￥578.00	登錄后可見	- +
1 g	In-stock	￥858.00	登錄后可見	- +

規(guī)格

庫存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

500 mg

In-stock

￥578.00

登錄后可見

- +

1 g

In-stock

￥858.00

登錄后可見

- +

基本信息

英文名稱	Gemcitabine Base \| LY 188011 \| NSC 613327
中文名稱	吉西他濱
CAS號(hào)	95058-81-4
分子式	C9H11F2N3O4
分子量	263.2
外觀	White to off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Gemcitabine (formerly LY-188011, NSC-613327; LY188011, NSC613327; dFdC; dFdCyd; trade name: Gemzar), an approved antimetabolite anticancer drug, is a potent DNA synthesis inhibitor with potential antineoplastic activity. With IC50s of 50 nM, 40 nM, 18 nM, and 12 nM, respectively, it suppresses the growth of PANC1, MIAPaCa2, BxPC3, and Capan2 cells. Difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP) are the active metabolites of gemcitabine that are produced intracellularly. The deoxynucleotide pool available for DNA synthesis is reduced when dFdCDP inhibits ribonucleotide reductase.

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吉西他濱

95058-81-4 98+% In-stock

￥578.00 500 mg

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吉西他濱

Gemcitabine Base | LY 188011 | NSC 613327

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質(zhì)檢證書(COA)