| 英文名稱 | Vismodegib (GDC-0449) |
|---|---|
| 中文名稱 | 維莫德吉 |
| CAS號 | 879085-55-9 |
| 分子式 | C19H14Cl2N2O3S |
| 分子量 | 421.30 |
| 外觀 | Off-white powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名稱 | Vismodegib (GDC-0449) |
|---|---|
| 中文名稱 | 維莫德吉 |
| CAS號 | 879085-55-9 |
| 分子式 | C19H14Cl2N2O3S |
| 分子量 | 421.30 |
| 外觀 | Off-white powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.